Anita has always had a great appreciation for country music. Her biggest musical influences include artists like: Barbara Mandrell, Connie Smith, Patsy Cline, Don Williams, and Buck Owens.
She took an interest in music at an early age, and with the encouragement of her parents, she began singing in the children's church choir.
She began taking piano lessons at the age of nine, and started singing professionally at the age of eleven when she and her brother, Brent Stapleton, became members of a Country/Gospel band, and began performing at local churches, county fairs, and outdoor festivals throughout their home state of Pennsylvania.
At the age of twelve, she became a regular performer on a local, live radio show called, "The Appalachian Jubilee", and she and her brother stepped into the recording studio for the first time when Brent was sixteen and Anita was thirteen.
In the years that followed, she and Brent formed a group of their own, and began performing at various venues in the surrounding states of Maryland, Delaware, New York, West Virginia and Ohio, where she gained more stage experience, and opened for such country artists as: Jean Shepard, Marty Stuart, Ricky Skaggs, Buck Trent, Jerry Reed, Boxcar Willie, Ferlin Husky, Eddie Rabbitt, Little Jimmy Dickens, Billy Walker, Melba Montgomery, McBride & The Ride, Tanya Tucker, Sammy Kershaw, and Jerry Reed.
At the age of eighteen, Anita started performing on a regular basis at the WWVA Wheeling Jamboree, in Wheeling, West Virginia. On that stage, she opened up for artists like: Tom T. Hall, Tammy Wynette, T.G. Shepherd, Ronnie Milsap, Gary Morris, Bill Anderson, Crystal Gayle and Pam Tillis.
In 1995, she wanted to further pursue her music career and moved to Nashville, and in the summer of 1997, she began touring on the road as a background vocalist for country artist Patty Loveless, and continued doing so until December of 1998, when Patty took a hiatus from touring.
On stage, Anita has done background vocalist work for several artists throughout the years, including working some road dates with singer, Sonya Issacs. She's also done background vocal work on stage with artists like: Connie Smith, Merle Kilgore, Jeanne Pruett, and Tommy Cash. Back in 2009, she was a part of a background vocal group for the "Inspirational Country Music Awards", which was featured on the Gospel network, TBN, and that night, she had the opportunity to sing harmony vocals with Charlie Daniels, Collin Raye, and Lee Greenwood.
In the recording studio, Anita has been included on projects by several artists, including: Betty Jean Robinson, Carroll Roberson, Moe Bandy, Jack Greene, Sheb Wooley, and Cowboy Jack Clement.
She has made several television show appearances over the years, including: "Grand Ole Opry Live", "Live With Regis & Kathie Lee", "Austin City Limits", "Late Night With Conan O'Brien", "Tennessee Mornings - Fox 17 Nashville", "The Inspirational Country Music Awards", "The Marty Stuart Show", "Good Day PA", and "Larry's Country Diner", and has hosted the Ernest Tubb Midnight Jamboree several times over the years, which airs on 650 AM - WSM radio.
From 2010-2014, Anita worked behind the scenes on "The Marty Stuart Show" as the "Guest Liaison".
From 2011-2014, Anita performed on Saturday afternoons at the downtown Nashville Ernest Tubb Record Shop with legendary guitarist and former Texas Troubadour, Leon Rhodes.
From January of 2016 - January of 2018, Anita hosted her own radio program called, "You're Lookin' At Country" on WWOV-FM in Wheeling, West Virginia.
In 2017, Anita and her dog, Abbie, were featured in the TV promotional ads for Governor Mike Huckabee's television show, "Huckabee".
Currently, she is performing in the Nashville area, at various venues, and continues to perform with her brother, Brent Stapleton, as often as she can.